Science and Research

The Science and Research Behind Exosomes: Elevating Skincare at Alora Aesthetic™

At Alora Aesthetic™, we firmly believe that the benefits of exosomes are not just a concept, but a scientific reality that can transform your skincare experience.

Our commitment to delivering exceptional results is rooted in the meticulous research and profound scientific understanding of exosomes and other biologic ingredients that can help rejuvenate and replenish. We invite you to peruse peer-reviewed papers and learn more about the benefits of exosomes firsthand. Don't take our word for it; see for yourself how Alora Aesthetic combines advanced scientific principles with groundbreaking discoveries to offer you a pathway to radiant, healthy, and ageless skin.

Our Alora EXO™ exosome-rich formulation is the only one characterized with a peer -reviewed published study.

  1. Gupta, A., Cady, C., Fauser, A., Rodriguez, H. C., Mistovich, R. J., Potty, A. G., & Maffulli, N. (2020). Cell-free Stem Cell-Derived Extract Formulation for regenerative medicine applications. International Journal of Molecular Sciences, 21(24), 9364. https://doi.org/10.3390/ijms21249364

  2. Thakur, A., Shah, D., Rai, D., Parra, D. C., Pathikonda, S., Kurilova, S. A., & Cili, A. (2023b). Therapeutic values of exosomes in cosmetics, skin care, tissue regeneration, and dermatological diseases. Cosmetics, 10(2), 65. https://doi.org/10.3390/cosmetics10020065

  3. Yang, G. H., Lee, Y. B., Kang, D., Choi, E., Nam, Y., Lee, K. H., You, H., Kang, H. J., An, S. H., & Jeon, H. (2021). Overcome the barriers of the skin: exosome therapy. Biomaterials Research, 25(1). https://doi.org/10.1186/s40824-021-00224-8

  4. Thakur A, Shah D, Rai D, Parra DC, Pathikonda S, Kurilova S, Cili A. Therapeutic Values of Exosomes in Cosmetics, Skin Care, Tissue Regeneration, and Dermatological Diseases. Cosmetics. 2023; 10(2):65. https://doi.org/10.3390/cosmetics10020065

  5. Thakur A, Shah D, Rai D, Parra DC, Pathikonda S, Kurilova S, Cili A. Therapeutic Values of Exosomes in Cosmetics, Skin Care, Tissue Regeneration, and Dermatological Diseases. Cosmetics. 2023; 10(2):65. https://doi.org/10.3390/cosmetics10020065

  6. Yang, G. H., Lee, Y. B., Kang, D., Choi, E., Nam, Y., Lee, K. H., You, H., Kang, H. J., An, S. H., & Jeon, H. (2021). Overcome the barriers of the skin: exosome therapy. Biomaterials Research, 25(1). https://doi.org/10.1186/s40824-021-00224-8

  7. Singh, A., & Yadav, S. (2016). Microneedling: Advances and widening horizons. Indian dermatology online journal, 7(4), 244–254. https://doi.org/10.4103/2229-5178.185468

  8. Yang, G. H., Lee, Y. B., Kang, D., Choi, E., Nam, Y., Lee, K. H., You, H., Kang, H. J., An, S. H., & Jeon, H. (2021). Overcome the barriers of the skin: exosome therapy. Biomaterials Research, 25(1). https://doi.org/10.1186/s40824-021-00224-8

  9. Quinlan, D. J., Ghanem, A. M., & Hassan, H. (2023). Topical growth factor preparations for facial skin rejuvenation: A systematic review. Journal of cosmetic dermatology, 22(7), 2023–2039. https://doi.org/10.1111/jocd.15644

  10. Miller-Kobisher, B., Suárez-Vega, D. V., & Velazco de Maldonado, G. J. (2021). Epidermal Growth Factor in Aesthetics and Regenerative Medicine: Systematic Review. Journal of cutaneous and aesthetic surgery, 14(2), 137–146. https://doi.org/10.4103/JCAS.JCAS_25_20

  11. Naughton GK, Jiang LI, Makino ET, Chung R, Nguyen A, Cheng T, Kadoya K, Mehta RC. Targeting Multiple Hallmarks of Skin Aging: Preclinical and Clinical Efficacy of a Novel Growth Factor-Based Skin Care Serum. Dermatol Ther (Heidelb). 2023 Jan;13(1):169-186. doi: 10.1007/s13555-022-00839-2. Epub 2022 Nov 14. PMID: 36374431; PMCID: PMC9823186.

 Additional Resources

  • Hajialiasgary Najafabadi, A., Soheilifar, M. H., & Masoudi-Khoram, N. (2024). Exosomes in skin photoaging: biological functions and therapeutic opportunity. Cell communication and signaling : CCS, 22(1), 32. https://doi.org/10.1186/s12964-023-01451-3

  • Zhang, B., Gong, J., He, L., Khan, A., Xiong, T., Shen, H., & Li, Z. (2022). Exosomes based advancements for application in medical aesthetics. Frontiers in bioengineering and biotechnology, 10, 1083640. https://doi.org/10.3389/fbioe.2022.1083640

  •  Tienda-Vázquez, M. A., Hanel, J. M., Márquez-Arteaga, E. M., Salgado-Álvarez, A. P., Scheckhuber, C. Q., Alanis-Gómez, J. R., Espinoza-Silva, J. I., Ramos-Kuri, M., Hernández-Rosas, F., Melchor-Martínez, E. M., & Parra-Saldívar, R. (2023). Exosomes: A Promising Strategy for Repair, Regeneration and Treatment of Skin Disorders. Cells, 12(12), 1625. https://doi.org/10.3390/cells12121625

  • Yoon-Jin Kim, Sae mi Yoo, Hwan Hee Park, Hye Jin Lim, Yu-Lee Kim, Seunghee Lee, Kwang-Won Seo, Kyung-Sun Kang, Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulates rejuvenation of human skin, Biochemical and Biophysical Research Communications, Volume 493, Issue 2, 2017, Pages 1102-1108, ISSN 0006-291X, https://doi.org/10.1016/j.bbrc.2017.09.056. (https://www.sciencedirect.com/science/article/pii/S0006291X1731817X)

  • Bakhtyar, N., Jeschke, M.G., Herer, E. et al. Exosomes from acellular Wharton’s jelly of the human umbilical cord promotes skin wound healing. Stem Cell Res Ther 9, 193 (2018). https://doi.org/10.1186/s13287-018-0921-2